Yasuyuki Sasaguri Selected Research

Histamine Receptors (Histamine Receptor)

12/2018	Relationship between CCL22 Expression by Vascular Smooth Muscle Cells and Macrophage Histamine Receptors in Atherosclerosis.
12/2016	Critical in vivo roles of histamine and histamine receptor signaling in animal models of metabolic syndrome.
7/2016	Novel function of histamine signaling via histamine receptors in cholesterol and bile acid metabolism: Histamine H2 receptor protects against nonalcoholic fatty liver disease.
2/2015	Novel function of histamine signaling in hyperlipidemia-induced atherosclerosis: Histamine H1 receptors protect and H2 receptors accelerate atherosclerosis.
9/2013	Histamine receptors expressed in circulating progenitor cells have reciprocal actions in ligation-induced arteriosclerosis.
4/2011	Histamine deficiency decreases atherosclerosis and inflammatory response in apolipoprotein E knockout mice independently of serum cholesterol level.
8/2010	Histamine regulation in glucose and lipid metabolism via histamine receptors: model for nonalcoholic steatohepatitis in mice.
3/2010	[Role of histamine in atherosclerotic lesions].
2/2005	Granulocyte macrophage-colony stimulating factor increases the expression of histamine and histamine receptors in monocytes/macrophages in relation to arteriosclerosis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Yasuyuki Sasaguri Research Topics

Disease

21	Atherosclerosis 12/2018 - 01/2004
20	Neoplasms (Cancer) 01/2019 - 01/2003
11	Inflammation (Inflammations) 12/2018 - 01/2005
6	Hyperlipidemias (Hyperlipidemia) 02/2015 - 08/2010
5	Atherosclerotic Plaque (Atheroma) 12/2016 - 05/2005
4	Carcinoma (Carcinomatosis) 01/2018 - 01/2003
4	Non-alcoholic Fatty Liver Disease 07/2016 - 08/2010
4	Fibrosis (Cirrhosis) 03/2014 - 09/2002
4	Vascular System Injuries 02/2013 - 05/2005
4	Neointima 05/2008 - 05/2005
3	Necrosis 01/2019 - 08/2012
3	Neoplasm Metastasis (Metastasis) 01/2016 - 05/2011
3	Adenocarcinoma 02/2015 - 05/2003
3	Arteriosclerosis 09/2013 - 02/2005
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 12/2016 - 12/2013
2	Squamous Cell Carcinoma of Head and Neck 01/2016 - 12/2015
2	Myocardial Infarction 05/2015 - 04/2008
2	Thrombocytopenia (Thrombopenia) 05/2015 - 10/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 05/2015 - 06/2009
2	Insulin Resistance 12/2013 - 08/2010
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2012 - 11/2010
2	Rheumatoid Arthritis 03/2011 - 10/2004
2	Hypoxia (Hypoxemia) 03/2011 - 10/2008
2	Aneurysm (Aneurysms) 12/2008 - 04/2006
2	Colonic Neoplasms (Colon Cancer) 09/2006 - 05/2004
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2006 - 01/2005
2	Small Cell Carcinoma 01/2003 - 02/2002
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2003 - 02/2002
1	Melanoma (Melanoma, Malignant) 01/2019
1	Skin Ulcer 01/2019
1	Adenocarcinoma of Lung 08/2016
1	Disease Progression 01/2016
1	Thrombotic Thrombocytopenic Purpura 05/2015
1	Chest Pain (Chest Pains) 05/2015
1	Ischemia 05/2015
1	Cardiac Arrhythmias (Arrythmia) 05/2015
1	Sudden Death 05/2015
1	Myxoma (Myxomas) 06/2014
1	Ulcerative Colitis 01/2014
1	Ulcer 01/2014
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2014

Drug/Important Bio-Agent (IBA)

17	Histamine (Histamine Dihydrochloride)FDA Link 12/2018 - 01/2004
10	CholesterolIBA 07/2016 - 05/2005
9	Histamine Receptors (Histamine Receptor)IBA 12/2018 - 02/2005
7	ApolipoproteinsIBA 02/2015 - 05/2005
6	EnzymesIBA 05/2015 - 06/2004
6	Proteins (Proteins, Gene)FDA Link 06/2012 - 05/2004
6	Histidine DecarboxylaseIBA 04/2011 - 01/2003
6	Matrix Metalloproteinases (MMPs)IBA 06/2010 - 10/2002
5	ParaffinIBA 08/2016 - 02/2013
4	Protein Isoforms (Isoforms)IBA 08/2016 - 07/2005
4	PeroxiredoxinsIBA 01/2016 - 10/2008
4	Apolipoproteins E (ApoE)IBA 02/2015 - 04/2011
4	Glucose (Dextrose)FDA LinkGeneric 06/2014 - 08/2010
3	CytokinesIBA 12/2018 - 01/2004
3	AntioxidantsIBA 01/2016 - 10/2008
3	MAP Kinase Kinase Kinase 5IBA 03/2014 - 07/2011
3	Streptozocin (Streptozotocin)FDA Link 12/2013 - 11/2010
3	Nitric Oxide Synthase (NO Synthase)IBA 01/2010 - 07/2005
2	CollagenIBA 01/2019 - 11/2012
2	Histamine H1 Receptors (Histamine H1 Receptor)IBA 12/2016 - 02/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2016 - 11/2012
2	Polypeptide N-acetylgalactosaminyltransferaseIBA 01/2016 - 12/2015
2	Biomarkers (Surrogate Marker)IBA 01/2016 - 05/2008
2	SurvivinIBA 02/2015 - 04/2011
2	Chemokine CCL22IBA 01/2015 - 10/2012
2	LipidsIBA 12/2013 - 09/2010
2	AntibodiesIBA 11/2011 - 01/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2010 - 06/2009
2	LDL CholesterolIBA 09/2010 - 01/2005
2	Histidine (L-Histidine)FDA Link 03/2010 - 06/2004
2	Matrix Metalloproteinase 12IBA 05/2008 - 04/2006
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 02/2008 - 02/2005
2	Superoxide DismutaseIBA 01/2008 - 07/2006
2	CarrageenanIBA 10/2004 - 06/2004
1	VimentinIBA 01/2018
1	Peptides (Polypeptides)IBA 08/2016
1	N-AcetylgalactosaminyltransferasesIBA 08/2016
1	UDP-N-acetylgalactosamine polypeptide N-acetylgalactosaminyltransferase 6IBA 08/2016
1	GlycosyltransferasesIBA 08/2016
1	Bile Acids and Salts (Bile Acids)IBA 07/2016
1	Choline (Choline Chloride)IBA 01/2016
1	Methionine (L-Methionine)FDA Link 01/2016
1	von Willebrand FactorIBA 05/2015
1	thiamine triphosphorate (TTP)IBA 05/2015
1	Histamine H2 ReceptorsIBA 02/2015
1	HMGB2 ProteinIBA 10/2014
1	HMGB1 Protein (HMG1)IBA 10/2014
1	ProdrugsIBA 01/2014
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2014
1	Dextran SulfateIBA 01/2014
1	ZonarolIBA 01/2014
1	hydroquinone (Esoterica)FDA Link 01/2014
1	Transaminases (Aminotransferases)IBA 12/2013
1	FructoseIBA 12/2013
1	Insulin (Novolin)FDA Link 12/2013
1	Adiponectin ReceptorsIBA 12/2013

Therapy/Procedure

5	Ligation 03/2014 - 12/2002
3	Therapeutics 10/2012 - 05/2003
1	Cell Transplantation 01/2019